methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate
Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate
CAS: 1235865-75-4
Molecular Formula: C17H23FN2O4
methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate - Names and Identifiers
methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate - Physico-chemical Properties
| Molecular Formula | C17H23FN2O4 |
| Molar Mass | 338.3739232 |
| Density | 1.377±0.06 g/cm3(Predicted) |
| Boling Point | 456.9±45.0 °C |
| pKa | 13.21±0.40(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Use | This product is an intermediate of ABT 199. ABT 199 is an effective selective BCL-2 inhibitor, which has strong anti-tumor activity while retaining platelets. Its practical application is to treat chronic lymphocytic leukemia cells and estrogen receptor positive breast cancer. |
methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate - Upstream Downstream Industry
methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate - Introduction
Open Data Unverified Data
ABT-199 (Venetoclax), unlike common cancer drugs, is a new type of drug that treats cancer by attacking an important protein called BCL-2. BCL-2 is one of the earliest discovered members of the cell death regulatory BCL-2 protein family. It is associated with many types of cancer, as well as some mental and autoimmune diseases. In cancer, it is thought to act as a suppressor that can help cancer cells resist cancer treatment drugs.
Last Update：2022-06-27 18:40:46
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Product Name: methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate Request for quotation
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Product Name: Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate Visit Supplier Webpage Request for quotation
CAS: 1235865-75-4
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CAS: 1235865-75-4
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CAS: 1235865-75-4
Tel: +86-571-88162785
Email: Lucy@verypharm.com
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Downstream Products for methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate
Methyl 2-[(1H-pyrrolo[2,3-b]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazin-1-yl]benzoate
2-[(1H-pyrrolo[2,3-B]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl ring Hex-1-enyl]methyl]piperazin-1-yl]benzoic acid
2-[(1H-pyrrolo[2,3-B]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl ring Hex-1-enyl]methyl]piperazin-1-yl]benzoic acid